A Unified Mechanistic Framework for Modeling Short- and Long-Acting siRNAs: Impact of RISC Stability on PD Durability
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Model-Informed Strategies for GLP-1 RA Development: Linking PKPD to Weight Loss and Glycemic Control
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From Xenograft to Clinic: QSP-guided dosing and step-up strategy for CD3×HLA-G T Cell Engagers TCE
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Clinical Efficacy and cytokine release syndrome (CRS) risk of CD3 Bispecifics in prostate cancer
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Leveraging in vitro data from novel drug candidates to prioritize antibody combinations in autoimmune disease using a QSP model of IBD
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QSP model to predict clinical PK/PD of siRNA therapeutics and learnings from model development
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QSP Platform for Predicting Alternate Priming Dose, Efficacy, and CRS Incidence in CD3 Bispecifics for STEAP1 Prostate Cancer
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A quantitative systems pharmacology (QSP) model framework for combined clinical efficacy and hematological toxicity predictions for antibody-drug conjugates
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A comprehensive multi-scale in silico approach for predicting antibody-drug conjugate clinical efficacy across oncological indications